Científicos descubren que células cancerígenas se hacen inmortales con vitamina C

155
919

Investigadores de la Universidad de Concepción en Chile han descubierto que las células cancerígenas satisfacen sus necesidades nutritivas y «se hacen inmortales» ingiriendo vitamina C reciclada, según afirmó la casa de estudios. La investigación fue publicada en la revista Free Radical Biology and Medicine.

Se trata de un mecanismo clave que esas células utilizan para sobrevivir, determinó el equipo, dirigido por la doctora Coralia Rivas y cuyo trabajo ha sido publicado recientemente por la prestigiosa revista

 

 –   [Accede aquí a la investigación completa]

Según la investigación, las células cancerígenas adquieren vitamina C oxidada (ácido deshidroascórbico o DHA), que se encuentra en altas concentraciones alrededor de tumores, la transporta a su interior y la convierte en vitamina C reducida, (AA, ácido ascórbico), que posee una función antioxidante.

«Descubrimos una característica inesperada de las células tumorales, que son capaces de acumular grandes cantidades de vitamina C en su interior, en comparación con las células normales«, declaró la doctora Rivas a la radio de la universidad.

«Probamos células tumorales provenientes de mamas, de próstata, de leucemia, y todas estas líneas celulares cumplían con esta característica«, subrayó la investigadora, para quien lo más importante es que ese mecanismo significa que la vitamina C, como es antioxidante, «estaría protegiendo a las células tumorales«.

Carola Muñoz, doctora en Ciencias Biológicas e integrante del equipo investigador, explicó en tanto que a diferencia de las células normales, las células tumorales tienen un transportador que toma esta vitamina C reducida y la lleva directo a la mitocondria (orgánulos encargados de suministrar la mayor parte de la energía necesaria para la actividad celular).

«Pensamos que es un mecanismo mediante el cual las células tumorales se hacen inmortales, a pesar de que estén rodeadas de señales oxidantes que, de otra forma, inducirían su muerte«, precisó.

El transportador, llamado SVCT2, «permitiría a la mitocondria del tumor trasladar la vitamina a su interior y, de esa forma, evitar la muerte de la célula cancerígena«, añadió Muñoz, que acotó que este transportador se sitúa dentro de la célula y no en la superficie, como era de esperar.

-Lo que se viene-

Para la doctora Rivas, el paso siguiente de la investigación es crear una solución farmacológica que inhiba el actuar de este método de transporte de la vitamina, lo que supone «continuar con la búsqueda de moléculas que puedan servir para bloquear el ingreso de vitamina C a la mitocondria«.

En esa línea, «el llamado no es a quitar la vitamina C de la dieta, sino que lo que hay que hacer es eliminar de la célula la capacidad para sobrevivir con ese mecanismo«, precisó Carola Muñoz.

La vitamina C «es un elemento fundamental para cualquier ser vivo, y en el caso de los humanos sí o sí debe estar en la dieta«, subrayó, y advirtió que al quitarla «más bien vas a causar una enfermedad sumamente complicada y vas a quedar desprotegido«.

Del descubrimiento, según Coralia Rivas, nace la posibilidad de crear nuevas terapias que busquen impedir la supervivencia de diferentes tipos de cáncer.

En Chile 62 personas mueren cada día a causa de algún tipo de cáncer, según datos oficiales, mientras en el Parlamento debate un proyecto que busca mejorar la financiación de los tratamientos contra esa enfermedad.

155 Comentarios

  1. I?m pleased, I should state. Really hardly ever do I encounter a blog that?s both informative and amusing, as well as let me tell you, you have struck the nail on the head. Your idea is outstanding; the problem is something that inadequate people are speaking smartly about. I am really delighted that I stumbled across this in my look for something connecting to this.

  2. There are definitely a lot of information like that to take into account. That is a terrific indicate bring up. I use the ideas above as basic motivation however plainly there are inquiries like the one you bring up where one of the most crucial point will certainly be working in truthful good faith. I don?t understand if best practices have emerged around things like that, but I am sure that your task is clearly determined as a level playing field. Both young boys and also ladies feel the impact of just a moment?s enjoyment, for the remainder of their lives.

  3. Good day! I could have sworn I’ve visited this web site before but after
    going through a few of the articles I realized it’s new to me.
    Anyhow, I’m definitely pleased I discovered
    it and I’ll be bookmarking it and checking back regularly!

  4. Have you ever thought about writing an e-book or guest authoring on other sites?
    I have a blog based upon on the same subjects
    you discuss and would really like to have you share some stories/information. I know my
    viewers would appreciate your work. If you’re even remotely interested, feel free to shoot me an e-mail.

  5. I think this is among the such a lot significant info for me.
    And i am happy studying your article. But should remark on few basic issues,
    The web site taste is ideal, the articles is truly excellent : D.
    Just right process, cheers

  6. The following time I check out a blog, I really hope that it doesn’t dissatisfy me as long as this. I suggest, I recognize it was my option to review, but I actually thought youd have something intriguing to state. All I hear is a bunch of grumbling regarding something that you could deal with if you werent as well active looking for interest.

  7. An outstanding share, I just offered this onto an associate who was doing a little analysis on this. As well as he as a matter of fact acquired me morning meal since I found it for him. smile. So let me reword that: Thnx for the reward! However yeah Thnkx for investing the time to discuss this, I feel highly regarding it as well as love finding out more on this topic. When possible, as you become expertise, would you mind updating your blog with more information? It is very practical for me. Large thumb up for this post!

  8. This design is spectacular! You most certainly know how to
    keep a reader entertained. Between your wit and your videos, I was almost moved to start
    my own blog (well, almost…HaHa!) Wonderful job.
    I really enjoyed what you had to say, and more than that, how you presented it.
    Too cool!

  9. Hi there, just became alert to your blog through Google, and found that it is really informative.
    I am gonna watch out for brussels. I’ll be grateful if you
    continue this in future. A lot of people will be benefited from your writing.
    Cheers!

  10. An interesting conversation is worth comment. I believe that you must compose extra on this topic, it may not be a taboo topic however generally people are inadequate to talk on such subjects. To the next. Cheers

  11. After research study a few of the blog posts on your website now, as well as I really like your way of blog writing. I bookmarked it to my book mark internet site list and also will be checking back quickly. Pls check out my website too as well as let me understand what you believe.

  12. Hey There. I discovered your weblog the usage of msn. That is a very neatly written article.
    I will be sure to bookmark it and return to read extra of your
    useful info. Thank you for the post. I will certainly comeback.

  13. What’s Happening i’m new to this, I stumbled upon this I have found It absolutely useful and it has
    helped me out loads. I’m hoping to give a contribution & help
    different users like its helped me. Great job.

  14. I am no longer sure the place you are getting your info, but
    good topic. I needs to spend some time finding out more
    or working out more. Thanks for wonderful info
    I was on the lookout for this info for my mission.

  15. Hey There. I discovered your blog the usage of msn. This is a very neatly written article.
    I’ll be sure to bookmark it and come back to read more of your helpful info.

    Thank you for the post. I’ll definitely return.

  16. I?m impressed, I should claim. Actually seldom do I encounter a blog that?s both educative as well as amusing, as well as let me tell you, you have hit the nail on the head. Your suggestion is exceptional; the problem is something that not nearly enough people are speaking intelligently about. I am really satisfied that I came across this in my look for something connecting to this.

  17. Do you mind if I quote a couple of your articles as long as I provide
    credit and sources back to your weblog? My blog is in the very same area of interest as yours and my visitors would genuinely benefit from a lot of the information you present here.

    Please let me know if this alright with you. Many thanks!
    3aN8IMa cheap flights

  18. I like the helpful information you provide for your articles.
    I’ll bookmark your blog and check again here frequently. I am quite sure I will learn many
    new stuff right here! Best of luck for the following!

  19. Just wish to say your article is as astonishing. The clearness in your post is just excellent and i could assume you are an expert on this subject.
    Fine with your permission allow me to grab your RSS feed to keep up to date with forthcoming post.
    Thanks a million and please continue the enjoyable work.

  20. Simply wish to say your article is as astonishing.
    The clarity in your post is simply spectacular and i could assume
    you are an expert on this subject. Fine with your permission let me to grab
    your RSS feed to keep up to date with forthcoming post.
    Thanks a million and please continue the enjoyable work.

  21. Great post. I discover something much more challenging on various blogs daily. It will certainly constantly be stimulating to read material from other authors as well as practice a little something from their shop. I?d prefer to make use of some with the material on my blog site whether you don?t mind. Natually I?ll give you a link on your internet blog site. Thanks for sharing.

  22. A person necessarily lend a hand to make severely posts I
    would state. This is the first time I frequented your website page and up to now?
    I surprised with the research you made to make this actual post extraordinary.

    Fantastic task!

  23. Howdy would you mind letting me know which hosting company you’re using?
    I’ve loaded your blog in 3 completely different internet browsers and I must say this blog loads a lot faster then most.
    Can you suggest a good hosting provider at a honest price?
    Thanks, I appreciate it!

  24. I really like your blog.. very nice colors & theme. Did you make this website yourself or did you hire someone to do
    it for you? Plz respond as I’m looking to design my own blog and would like to find out where u got this from.

    thank you

  25. We absolutely love your blog and find most of your post’s to be exactly I’m looking for.
    can you offer guest writers to write content for you personally?
    I wouldn’t mind writing a post or elaborating on most of the subjects you write in relation to here.
    Again, awesome web log!

  26. With havin so much content do you ever run into any issues of plagorism or copyright infringement?

    My blog has a lot of completely unique content I’ve
    either authored myself or outsourced but it appears a lot
    of it is popping it up all over the web without my agreement.
    Do you know any ways to help protect against content from
    being stolen? I’d really appreciate it.

  27. This web site is really a walk-through for all of the info you desired concerning this as well as didn?t know who to ask. Peek below, as well as you?ll certainly find it.

  28. I’m not positive the place you’re getting your information, however great topic.
    I needs to spend a while learning more or working out more.

    Thanks for fantastic information I was on the lookout for this information for my mission.

  29. Hey there! I know this is somewhat off topic but I was wondering which blog platform are you
    using for this website? I’m getting sick and tired of
    Wordpress because I’ve had issues with hackers and I’m looking at
    alternatives for another platform. I would be great if you could point me in the direction of a good platform.

  30. You really make it seem so easy with your presentation but I
    find this topic to be really something that I think I would never understand.
    It seems too complicated and extremely broad for me. I’m looking forward for your next post, I’ll try
    to get the hang of it!

  31. Hi, I do think this is an excellent website. I stumbledupon it 😉 I may return once again since I book marked it. Money and freedom is the best way to change, may you be rich and continue to guide other people.

  32. Youre so amazing! I don’t expect Ive read anything like this prior to. So good to find somebody with some initial thoughts on this subject. realy thank you for beginning this up. this website is something that is required online, someone with a little creativity. beneficial task for bringing something new to the web!

  33. This internet site is really a walk-through for every one of the information you wanted regarding this as well as didn?t know that to ask. Glimpse below, and you?ll definitely uncover it.

  34. I blog often and I really thank you for your information. This article has truly peaked my interest.
    I am going to bookmark your site and keep checking for new details about once a week.

    I subscribed to your Feed too.

  35. This is the ideal blog site for anybody that intends to find out about this subject. You understand a lot its almost hard to suggest with you (not that I actually would want?HaHa). You definitely put a new spin on a topic thats been written about for many years. Fantastic things, simply wonderful!

  36. This internet site is truly a walk-through for every one of the details you desired regarding this and didn?t understand who to ask. Peek below, and also you?ll most definitely uncover it.

  37. Hello just wanted to give you a quick heads up. The text
    in your post seem to be running off the screen in Opera.
    I’m not sure if this is a format issue or something to do
    with browser compatibility but I thought I’d post to let you know.
    The style and design look great though! Hope you get the issue resolved soon. Thanks

  38. There are some interesting points in time in this post however I don?t recognize if I see all of them center to heart. There is some legitimacy but I will certainly take hold point of view until I look into it better. Excellent article, thanks and we want extra! Included in FeedBurner too

  39. Hi, Neat post. There is an issue along with your web site in web explorer,
    would check this? IE nonetheless is the marketplace leader
    and a big component of folks will pass over your great writing due to this problem.

  40. Aw, this was a really nice blog post. In concept I wish to place in creating similar to this additionally? requiring time and also actual effort to make a very good write-up? but what can I say? I put things off alot and also by no means seem to obtain something done.

  41. Youre so awesome! I do not expect Ive check out anything like this before. So nice to locate somebody with some original ideas on this subject. realy thanks for starting this up. this internet site is something that is required on the internet, someone with a little originality. helpful task for bringing something brand-new to the net!

  42. This web site is actually a walk-through for all of the info you wanted regarding this and also didn?t understand who to ask. Look right here, as well as you?ll certainly find it.

  43. I just want to tell you that I’m all new to blogs and absolutely liked your web page. Probably I’m going to bookmark your site . You actually have excellent article content. With thanks for sharing with us your web page.

  44. Please let me know if you’re looking for a article writer for your blog. You have some really good posts and I believe I would be a good asset. If you ever want to take some of the load off, I’d love to write some articles for your blog in exchange for a link back to mine. Please blast me an e-mail if interested. Thanks!|

  45. For newest news you have to pay a visit world wide web and on the web I found this website as a most excellent website for most up-to-date updates.|

  46. Having read this I believed it was rather informative. I appreciate you finding the time and energy to put this short article together. I once again find myself personally spending a significant amount of time both reading and leaving comments. But so what, it was still worthwhile!|

  47. What’s up, this weekend is fastidious designed for
    me, for the reason that this time i am reading this enormous educational piece of writing here at my
    home.

  48. Superb blog! Do you have any helpful hints for aspiring writers? I’m hoping to start my own site soon but I’m a little lost on everything. Would you advise starting with a free platform like WordPress or go for a paid option? There are so many choices out there that I’m totally confused .. Any suggestions? Bless you!|

  49. It is in point of fact a great and useful piece of info. I am glad that you shared this useful information with us. Please keep us informed like this. Thank you for sharing.|

  50. Hi there! This article couldn’t be written much better! Looking through this post reminds me of my previous roommate! He continually kept preaching about this. I am going to forward this post to him. Pretty sure he’ll have a very good read. Many thanks for sharing!|

  51. Please let me know if you’re looking for a writer for your site. You have some really great articles and I believe I would be a good asset. If you ever want to take some of the load off, I’d really like to write some material for your blog in exchange for a link back to mine. Please shoot me an e-mail if interested. Regards!|

  52. Free Rehab Programs http://aaa-rehab.com Drug Rehab http://aaa-rehab.com Drug And Rehab
    http://aaa-rehab.com